I spend all sorts of time when I'm doing my blog posts to make sure that things are laid out well... I publish what I've done and then go to look at the blog entry, then go back to edit it so that things are where I want them, then back to look at the blog entry. Some days I do this 4 or 5 times.
This afternoon, when I didn't have my bookmark bar on the left side of my screen I discovered that my blog posts only look good on my screen with the bookmark bar taking up some of the space. My careful editing doesn't matter... things are all screwy depending on what browser you are using or how big your screen is.
Guess that means I might as well stop trying to make it look pretty on my screen!